Landmark Mayo Clinic study finds stenting reduces stroke risk in people with carotid artery narrowing

A major international study led by Mayo Clinic researchers and funded by the National Institutes of Health found that for people with severe carotid artery narrowing who haven’t experienced recent stroke symptoms, a minimally invasive procedure called carotid artery stenting, combined with intensive medical therapy, significantly lowered stroke risk compared with medical therapy alone. Traditional surgery (carotid endarterectomy) did not show the same benefit. The research is published in The New England Journal of Medicine.

The Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2) is the largest study to date comparing current treatment approaches for this condition, caused by plaque buildup in the arteries supplying blood to the brain.

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